RRIG1 mediates effects of retinoic acid receptor beta2 on tumor cell growth and gene expression through binding to and inhibition of RhoA.

Liang, Zheng D; Lippman, Scott M; Wu, Tsung-Teh; Lotan, Reuben; Xu, Xiao-Chun

Liang, Zheng D; Lippman, Scott M; Wu, Tsung-Teh; Lotan, Reuben; Xu, Xiao-Chun.

Affiliation

Liang ZD; Department of Clinical Cancer Prevention, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

Cancer Res ; 66(14): 7111-8, 2006 Jul 15.

Article in En | MEDLINE | ID: mdl-16849557

Subject(s)

Esophageal Neoplasms/metabolism; Membrane Proteins/metabolism; Receptors, Retinoic Acid/metabolism; Tumor Suppressor Proteins/metabolism; rhoA GTP-Binding Protein/metabolism; Adenocarcinoma/genetics; Adenocarcinoma/metabolism; Amino Acid Sequence; Animals; Base Sequence; COS Cells; Carcinoma, Squamous Cell/genetics; Carcinoma, Squamous Cell/metabolism; Cell Growth Processes; Cell Line, Tumor; Chlorocebus aethiops; Cloning, Molecular; DNA, Complementary/genetics; Esophageal Neoplasms/genetics; Humans; Membrane Proteins/genetics; Molecular Sequence Data; RNA, Messenger/biosynthesis; RNA, Messenger/genetics; Receptors, Retinoic Acid/biosynthesis; Receptors, Retinoic Acid/genetics; Tumor Suppressor Proteins/genetics; rhoA GTP-Binding Protein/antagonists & inhibitors

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Database: MEDLINE Main subject: Esophageal Neoplasms / Receptors, Retinoic Acid / RhoA GTP-Binding Protein / Tumor Suppressor Proteins / Membrane Proteins Limits: Animals / Humans Language: En Year: 2006 Type: Article

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