Mycobacteria lacking the RD1 region do not induce necrosis in the lungs of mice lacking interferon-gamma.

Junqueira-Kipnis, Ana Paula; Basaraba, Randall J; Gruppo, Veronica; Palanisamy, Gopinath; Turner, Oliver C; Hsu, Tsungda; Jacobs, William R; Fulton, Scott A; Reba, Scott M; Boom, W Henry; Orme, Ian M

Junqueira-Kipnis, Ana Paula; Basaraba, Randall J; Gruppo, Veronica; Palanisamy, Gopinath; Turner, Oliver C; Hsu, Tsungda; Jacobs, William R; Fulton, Scott A; Reba, Scott M; Boom, W Henry; Orme, Ian M.

Affiliation

Junqueira-Kipnis AP; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA.

Immunology ; 119(2): 224-31, 2006 Oct.

Article in En | MEDLINE | ID: mdl-17005003

Subject(s)

Interferon-gamma/immunology; Lung/pathology; Mycobacterium bovis/pathogenicity; Mycobacterium tuberculosis/pathogenicity; Tuberculosis/immunology; Animals; Bacterial Proteins/genetics; Bacterial Proteins/immunology; CD4-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/immunology; Cell Movement/immunology; Disease Progression; Female; Genes, Bacterial; Interferon-gamma/deficiency; Interferon-gamma/genetics; Lung/microbiology; Lymphocyte Activation/immunology; Macrophage Activation/immunology; Mice; Mice, Inbred C57BL; Mice, Knockout; Mycobacterium bovis/genetics; Mycobacterium bovis/growth & development; Mycobacterium tuberculosis/genetics; Mycobacterium tuberculosis/growth & development; Necrosis; Tuberculosis/microbiology; Virulence

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Full text: 1 Database: MEDLINE Main subject: Tuberculosis / Interferon-gamma / Lung / Mycobacterium bovis / Mycobacterium tuberculosis Limits: Animals Language: En Year: 2006 Type: Article

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