Cholecalciferol (vitamin D3) and the retinoid N-(4-hydroxyphenyl)retinamide (4-HPR) are synergistic for chemoprevention of prostate cancer.

Tokar, Erik J; Ancrile, Brooke B; Ablin, Richard J; Webber, Mukta M

Tokar, Erik J; Ancrile, Brooke B; Ablin, Richard J; Webber, Mukta M.

Affiliation

Tokar EJ; Department of Zoology, Michigan State University, East Lansing 48824, USA. tokare@niehs.nih.gov

J Exp Ther Oncol ; 5(4): 323-33, 2006.

Article in En | MEDLINE | ID: mdl-17024972

Subject(s)

Anticarcinogenic Agents/pharmacology; Cholecalciferol/pharmacology; Drug Synergism; Fenretinide/pharmacology; Gene Expression Regulation, Neoplastic; Prostatic Neoplasms/drug therapy; Humans; Male; Matrix Metalloproteinase 2/metabolism; Prostatic Neoplasms/metabolism; Prostatic Neoplasms/therapy; Retinoids/metabolism; Up-Regulation; Vimentin/metabolism; Vitamins/metabolism

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Database: MEDLINE Main subject: Prostatic Neoplasms / Gene Expression Regulation, Neoplastic / Anticarcinogenic Agents / Fenretinide / Cholecalciferol / Drug Synergism Limits: Humans / Male Language: En Year: 2006 Type: Article

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