Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1alpha.

Piessen, Guillaume; Jonckheere, Nicolas; Vincent, Audrey; Hémon, Brigitte; Ducourouble, Marie-Paule; Copin, Marie-Christine; Mariette, Christophe; Van Seuningen, Isabelle

Piessen, Guillaume; Jonckheere, Nicolas; Vincent, Audrey; Hémon, Brigitte; Ducourouble, Marie-Paule; Copin, Marie-Christine; Mariette, Christophe; Van Seuningen, Isabelle.

Affiliation

Piessen G; Unité INSERM 560, Place de Verdun, 59045 Lille Cedex, France.

Biochem J ; 402(1): 81-91, 2007 Feb 15.

Article in En | MEDLINE | ID: mdl-17037983

Subject(s)

Esophageal Neoplasms/genetics; Gene Expression Regulation, Neoplastic; Hepatocyte Nuclear Factor 1-alpha/metabolism; Mucins/genetics; Taurochenodeoxycholic Acid/pharmacology; Taurodeoxycholic Acid/pharmacology; Bile Reflux/metabolism; Cell Line, Tumor; Esophageal Neoplasms/metabolism; Hepatocyte Nuclear Factor 4/genetics; Hepatocyte Nuclear Factor 4/metabolism; Humans; Immunohistochemistry; Mucin-4; Mucins/metabolism; Promoter Regions, Genetic; RNA, Small Interfering/metabolism; Transcription, Genetic; Transfection; Up-Regulation

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Full text: 1 Database: MEDLINE Main subject: Taurochenodeoxycholic Acid / Taurodeoxycholic Acid / Esophageal Neoplasms / Gene Expression Regulation, Neoplastic / Hepatocyte Nuclear Factor 1-alpha / Mucins Type of study: Prognostic_studies Limits: Humans Language: En Year: 2007 Type: Article

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