Physiologic regulation of a tetrodotoxin-sensitive sodium influx that mediates a slow afterdepolarization potential in gonadotropin-releasing hormone neurons: possible implications for the central regulation of fertility.

Chu, Zhiguo; Moenter, Suzanne M

Chu, Zhiguo; Moenter, Suzanne M.

Affiliation

Chu Z; Department of Medicine, University of Virginia, Charlottesville, Virginia 22908, USA.

J Neurosci ; 26(46): 11961-73, 2006 Nov 15.

Article in En | MEDLINE | ID: mdl-17108170

Subject(s)

Anterior Hypothalamic Nucleus/metabolism; Fertility/physiology; Gonadotropin-Releasing Hormone/metabolism; Neurons/metabolism; Preoptic Area/metabolism; Sodium Channels/metabolism; Action Potentials/drug effects; Action Potentials/physiology; Animals; Anterior Hypothalamic Nucleus/cytology; Anterior Hypothalamic Nucleus/drug effects; Calcium Channel Blockers/pharmacology; Calcium Channels/drug effects; Calcium Channels/metabolism; Estradiol/metabolism; Estrous Cycle/drug effects; Estrous Cycle/physiology; Feedback, Physiological/physiology; Female; Fertility/drug effects; Mice; Neurons/cytology; Neurons/drug effects; Organ Culture Techniques; Ovariectomy; Patch-Clamp Techniques; Preoptic Area/cytology; Preoptic Area/drug effects; Reaction Time/drug effects; Reaction Time/physiology; Receptors, Neurotransmitter/antagonists & inhibitors; Receptors, Neurotransmitter/metabolism; Sodium Channel Blockers/pharmacology; Sodium Channels/drug effects; Tetrodotoxin/pharmacology

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Full text: 1 Database: MEDLINE Main subject: Preoptic Area / Sodium Channels / Gonadotropin-Releasing Hormone / Fertility / Anterior Hypothalamic Nucleus / Neurons Type of study: Diagnostic_studies Limits: Animals Language: En Year: 2006 Type: Article

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