Penicillium piceum infection: diagnosis and successful treatment in chronic granulomatous disease.
Med Mycol
; 44(8): 749-53, 2006 Dec.
Article
in En
| MEDLINE
| ID: mdl-17127632
ABSTRACT
Infections due to Penicillium species other than P.marneffei are rare. We identified a boy with X-linked chronic granulomatous disease (X-CGD) with a pulmonary nodule and adjacent rib osteomyelitis caused by Penicillium piceum. The only sign of infection was an elevated sedimentation rate. P. piceum was isolated by fine needle aspirate and from excised infected tissues. Surgical removal and one year of voriconazole treatment were very well tolerated and led to complete recovery. Microbiological, microscopic and molecular studies support the fungal diagnosis. P. piceum should be considered as a relevant pathogen in immunocompromised patients.
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Database:
MEDLINE
Main subject:
Osteomyelitis
/
Penicillium
/
Genetic Diseases, X-Linked
/
Granulomatous Disease, Chronic
/
Mycoses
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Child
/
Humans
/
Male
Language:
En
Year:
2006
Type:
Article