Endomorphin 1 activates nitric oxide synthase 2 activity and downregulates nitric oxide synthase 2 mRNA expression.

Saric, A; Balog, T; Sobocanec, S; Marotti, T

Saric, A; Balog, T; Sobocanec, S; Marotti, T.

Affiliation

Saric A; Division of Molecular Medicine, Rudjer Boskovic Institute, Bijenicka 54, 10000 Zagreb, Croatia.

Neuroscience ; 144(4): 1454-61, 2007 Feb 23.

Article in En | MEDLINE | ID: mdl-17197099

Subject(s)

Macrophages/enzymology; Nitric Oxide Synthase Type II/metabolism; Nitric Oxide/biosynthesis; Oligopeptides/metabolism; RNA, Messenger/metabolism; Up-Regulation/physiology; Animals; Cell Line; Dose-Response Relationship, Drug; Down-Regulation/drug effects; Down-Regulation/physiology; Enzyme Activation/drug effects; Enzyme Activation/physiology; Enzyme Inhibitors/pharmacology; Gene Expression Regulation, Enzymologic/physiology; Lipopolysaccharides/pharmacology; Macrophages/drug effects; Mice; Narcotic Antagonists/pharmacology; Nitric Oxide Synthase Type II/drug effects; Nitric Oxide Synthase Type II/genetics; Oligopeptides/pharmacology; RNA, Messenger/drug effects; Receptors, Opioid, mu/agonists; Receptors, Opioid, mu/antagonists & inhibitors; Receptors, Opioid, mu/metabolism; Up-Regulation/drug effects

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Database: MEDLINE Main subject: Oligopeptides / RNA, Messenger / Up-Regulation / Nitric Oxide Synthase Type II / Macrophages / Nitric Oxide Limits: Animals Language: En Year: 2007 Type: Article

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