Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma.

Peacock, Craig D; Wang, Qiuju; Gesell, Gregory S; Corcoran-Schwartz, Ian M; Jones, Evan; Kim, Jynho; Devereux, Wendy L; Rhodes, Jonathan T; Huff, Carol A; Beachy, Philip A; Watkins, D Neil; Matsui, William

Peacock, Craig D; Wang, Qiuju; Gesell, Gregory S; Corcoran-Schwartz, Ian M; Jones, Evan; Kim, Jynho; Devereux, Wendy L; Rhodes, Jonathan T; Huff, Carol A; Beachy, Philip A; Watkins, D Neil; Matsui, William.

Affiliation

Peacock CD; Sidney Kimmel Comprehensive Cancer Center and Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

Proc Natl Acad Sci U S A ; 104(10): 4048-53, 2007 Mar 06.

Article in En | MEDLINE | ID: mdl-17360475

Subject(s)

Hedgehog Proteins/physiology; Multiple Myeloma/pathology; Signal Transduction; Stem Cells/metabolism; Animals; Cell Line, Tumor; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Phenotype; Plasma Cells/metabolism; Syndecan-1/biosynthesis; Veratrum Alkaloids/pharmacology

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Stem Cells / Signal Transduction / Hedgehog Proteins / Multiple Myeloma Limits: Animals / Humans Language: En Year: 2007 Type: Article

Fulltext

XML

PubMed Links

Search on Google