By-passing immunization. Human antibodies from V-gene libraries displayed on phage.

Marks, J D; Hoogenboom, H R; Bonnert, T P; McCafferty, J; Griffiths, A D; Winter, G

Marks, J D; Hoogenboom, H R; Bonnert, T P; McCafferty, J; Griffiths, A D; Winter, G.

Affiliation

Marks JD; MRC Centre for Protein Engineering, Cambridge, U.K.

J Mol Biol ; 222(3): 581-97, 1991 Dec 05.

Article in En | MEDLINE | ID: mdl-1748994

Subject(s)

Bacteriophages/genetics; Gene Library; Immunoglobulin Variable Region/genetics; Lymphocytes/immunology; Protein Engineering; Amino Acid Sequence; Base Sequence; Binding Sites, Antibody/genetics; DNA, Single-Stranded; Gene Expression Regulation, Viral; Humans; Immunoglobulin Fragments/genetics; Immunoglobulin Variable Region/immunology; Immunoglobulin kappa-Chains/genetics; Immunoglobulin lambda-Chains/genetics; Molecular Sequence Data; Mutation/genetics; Sequence Homology, Nucleic Acid

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Database: MEDLINE Main subject: Bacteriophages / Immunoglobulin Variable Region / Lymphocytes / Protein Engineering / Gene Library Limits: Humans Language: En Year: 1991 Type: Article

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