Involvement of glucocorticoid receptor and pregnane X receptor in the regulation of mouse CYP3A44 female-predominant expression by glucocorticoid hormone.

Bhadhprasit, Wattanaporn; Sakuma, Tsutomu; Hatakeyama, Nobuyuki; Fuwa, Masahiro; Kitajima, Kaori; Nemoto, Nobuo

Bhadhprasit, Wattanaporn; Sakuma, Tsutomu; Hatakeyama, Nobuyuki; Fuwa, Masahiro; Kitajima, Kaori; Nemoto, Nobuo.

Affiliation

Bhadhprasit W; Department of Toxicology, Graduate School of Medical and Pharmaceutical Sciences, University of Toyama, Sugitani, Toyama, Japan.

Drug Metab Dispos ; 35(10): 1880-5, 2007 Oct.

Article in En | MEDLINE | ID: mdl-17640954

Subject(s)

Cytochrome P-450 Enzyme System/genetics; Dexamethasone/pharmacology; Glucocorticoids/pharmacology; Receptors, Glucocorticoid/genetics; Receptors, Steroid/genetics; Animals; Cells, Cultured; Corticosterone/pharmacology; Female; Gene Expression Regulation/drug effects; Hepatocytes/drug effects; Hepatocytes/metabolism; Hydrocortisone/pharmacology; Male; Mice; Mice, Inbred C57BL; Pregnane X Receptor; RNA, Messenger/metabolism

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Database: MEDLINE Main subject: Dexamethasone / Receptors, Glucocorticoid / Receptors, Steroid / Cytochrome P-450 Enzyme System / Glucocorticoids Limits: Animals Language: En Year: 2007 Type: Article

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