Mycobacterium tuberculosis nuoG is a virulence gene that inhibits apoptosis of infected host cells.

Velmurugan, Kamalakannan; Chen, Bing; Miller, Jessica L; Azogue, Sharon; Gurses, Serdar; Hsu, Tsungda; Glickman, Michael; Jacobs, William R; Porcelli, Steven A; Briken, Volker

Velmurugan, Kamalakannan; Chen, Bing; Miller, Jessica L; Azogue, Sharon; Gurses, Serdar; Hsu, Tsungda; Glickman, Michael; Jacobs, William R; Porcelli, Steven A; Briken, Volker.

Affiliation

Velmurugan K; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, United States of America.

PLoS Pathog ; 3(7): e110, 2007 Jul.

Article in En | MEDLINE | ID: mdl-17658950

Subject(s)

Apoptosis/genetics; Gene Expression Regulation, Bacterial; Genes, Bacterial; Host-Pathogen Interactions; Mycobacterium tuberculosis/genetics; NADH Dehydrogenase/genetics; Animals; Base Sequence; Cell Line; Female; Gene Silencing; Humans; Macrophages/microbiology; Macrophages/pathology; Mice; Mice, Inbred BALB C; Mice, SCID; Molecular Sequence Data; Monocytes/metabolism; Monocytes/microbiology; Monocytes/pathology; Mycobacterium tuberculosis/enzymology; Mycobacterium tuberculosis/pathogenicity; NADH Dehydrogenase/metabolism; NADPH Dehydrogenase/metabolism; Virulence

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Full text: 1 Database: MEDLINE Main subject: Gene Expression Regulation, Bacterial / Apoptosis / Host-Pathogen Interactions / Genes, Bacterial / Mycobacterium tuberculosis / NADH Dehydrogenase Limits: Animals / Female / Humans Language: En Year: 2007 Type: Article

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