Possible role of MDR1 two-locus genotypes for young-age onset ulcerative colitis but not Crohn's disease.

Fiedler, T; Büning, C; Reuter, W; Pitre, G; Gentz, E; Schmidt, H H; Büttner, J; Ockenga, J; Gerloff, T; Meisel, C; Lochs, H; Roots, I; Köpke, K; Johne, A

Fiedler, T; Büning, C; Reuter, W; Pitre, G; Gentz, E; Schmidt, H H; Büttner, J; Ockenga, J; Gerloff, T; Meisel, C; Lochs, H; Roots, I; Köpke, K; Johne, A.

Affiliation

Fiedler T; Department of Gastroenterology, Hepatology & Endocrinology, Charité - Universitätsmedizin Berlin, CCM, Charitéplatz 1, Berlin, 10117, Germany. thomas.fiedler@charite.de

Eur J Clin Pharmacol ; 63(10): 917-25, 2007 Oct.

Article in En | MEDLINE | ID: mdl-17665184

Subject(s)

ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics; Colitis, Ulcerative/genetics; Crohn Disease/genetics; Polymorphism, Single Nucleotide; ATP Binding Cassette Transporter, Subfamily B; Adult; Age of Onset; Anti-Inflammatory Agents/therapeutic use; Case-Control Studies; Colitis, Ulcerative/drug therapy; Colitis, Ulcerative/epidemiology; Crohn Disease/drug therapy; Crohn Disease/epidemiology; Disease Progression; Female; Gene Frequency; Genetic Predisposition to Disease; Germany/epidemiology; Glucocorticoids/therapeutic use; Haplotypes; Humans; Linkage Disequilibrium; Male; Middle Aged; Odds Ratio; Phenotype; Retrospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Treatment Outcome

Search on Google

XML

PubMed Links

Database: MEDLINE Main subject: Colitis, Ulcerative / Crohn Disease / ATP Binding Cassette Transporter, Subfamily B, Member 1 / Polymorphism, Single Nucleotide Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Year: 2007 Type: Article

Search on Google

XML

PubMed Links