The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obesity-related traits in the Diabetes Prevention Program.

Franks, P W; Jablonski, K A; Delahanty, L; Hanson, R L; Kahn, S E; Altshuler, D; Knowler, W C; Florez, J C

Franks, P W; Jablonski, K A; Delahanty, L; Hanson, R L; Kahn, S E; Altshuler, D; Knowler, W C; Florez, J C.

Affiliation

Franks PW; Genetic Epidemiology and Clinical Research Group, Department of Public Health and Clinical Medicine, Section for Medicine, Umea University Hospital, Umea, Sweden.

Diabetologia ; 50(12): 2451-60, 2007 Dec.

Article in En | MEDLINE | ID: mdl-17898990

Subject(s)

Amino Acid Substitution; Chromans/therapeutic use; Diabetes Mellitus, Type 2/prevention & control; Metformin/therapeutic use; Obesity/genetics; PPAR gamma/genetics; Thiazolidinediones/therapeutic use; Adult; Alanine/genetics; Body Composition/drug effects; Body Composition/genetics; Diabetes Mellitus, Type 2/complications; Diabetes Mellitus, Type 2/genetics; Dietary Fats/administration & dosage; Eating/drug effects; Eating/genetics; Female; Gene Frequency; Genotype; Humans; Hypoglycemic Agents/therapeutic use; Life Style; Male; Middle Aged; Obesity/complications; Placebos; Proline/genetics; Troglitazone

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Full text: 1 Database: MEDLINE Main subject: Chromans / Amino Acid Substitution / Thiazolidinediones / PPAR gamma / Diabetes Mellitus, Type 2 / Metformin / Obesity Type of study: Clinical_trials Limits: Adult / Female / Humans / Male / Middle aged Language: En Year: 2007 Type: Article

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