Altered myocardial gene expression reveals possible maladaptive processes in heterozygous and homozygous cardiac myosin-binding protein C knockout mice.

Eijssen, L M T; van den Bosch, B J C; Vignier, N; Lindsey, P J; van den Burg, C M M; Carrier, L; Doevendans, P A; van der Vusse, G J; Smeets, H J M

Eijssen, L M T; van den Bosch, B J C; Vignier, N; Lindsey, P J; van den Burg, C M M; Carrier, L; Doevendans, P A; van der Vusse, G J; Smeets, H J M.

Affiliation

Eijssen LM; Department of Genetics and Cell Biology, Cardiovascular Research Institute Maastricht, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands.

Genomics ; 91(1): 52-60, 2008 Jan.

Article in En | MEDLINE | ID: mdl-18060737

Subject(s)

Cardiomyopathy, Hypertrophic, Familial/metabolism; Carrier Proteins/metabolism; Chromosome Disorders/metabolism; Gene Expression Regulation; Hypertrophy, Left Ventricular/metabolism; Myocardium/metabolism; Animals; Apoptosis/genetics; Cardiomyopathy, Hypertrophic, Familial/genetics; Cardiomyopathy, Hypertrophic, Familial/pathology; Carrier Proteins/genetics; Chromosome Disorders/genetics; Chromosome Disorders/pathology; Extracellular Signal-Regulated MAP Kinases; Gene Expression Profiling; Gene Expression Regulation/genetics; Heterozygote; Homozygote; Hypertrophy, Left Ventricular/genetics; Hypertrophy, Left Ventricular/pathology; MAP Kinase Kinase 4/genetics; MAP Kinase Kinase 4/metabolism; MAP Kinase Signaling System/genetics; Mice; Mice, Knockout; Myocardium/pathology; Oligonucleotide Array Sequence Analysis; Ventricular Septum/metabolism; Ventricular Septum/pathology; p38 Mitogen-Activated Protein Kinases/genetics; p38 Mitogen-Activated Protein Kinases/metabolism

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Database: MEDLINE Main subject: Carrier Proteins / Gene Expression Regulation / Hypertrophy, Left Ventricular / Chromosome Disorders / Cardiomyopathy, Hypertrophic, Familial / Myocardium Limits: Animals Language: En Year: 2008 Type: Article

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