Construction and validation of an automated flow hydrogenation instrument for application in high-throughput organic chemistry.

Clapham, Bruce; Wilson, Noel S; Michmerhuizen, Melissa J; Blanchard, David P; Dingle, David M; Nemcek, Thomas A; Pan, Jeffrey Y; Sauer, Daryl R

Clapham, Bruce; Wilson, Noel S; Michmerhuizen, Melissa J; Blanchard, David P; Dingle, David M; Nemcek, Thomas A; Pan, Jeffrey Y; Sauer, Daryl R.

Affiliation

Clapham B; High-Throughput Organic Synthesis and Automation Engineering, Department of Advanced Technology, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064, USA. bruce.clapham@abbott.com

J Comb Chem ; 10(1): 88-93, 2008.

Article in En | MEDLINE | ID: mdl-18095655

Subject(s)

Chemistry, Organic/instrumentation; Combinatorial Chemistry Techniques/instrumentation; Drug Design; Robotics; Catalysis; Chemistry, Organic/methods; Combinatorial Chemistry Techniques/methods; Equipment Design; Hydrogenation; Reproducibility of Results; Small Molecule Libraries/chemistry

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Database: MEDLINE Main subject: Robotics / Drug Design / Chemistry, Organic / Combinatorial Chemistry Techniques Type of study: Prognostic_studies Language: En Year: 2008 Type: Article

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