Nuclear-targeted chimeric vector enhancing nonviral gene transfer into skeletal muscle of Fabry mice in vivo.

Lavigne, Matthieu D; Yates, Laura; Coxhead, Peter; Górecki, Dariusz C

Lavigne, Matthieu D; Yates, Laura; Coxhead, Peter; Górecki, Dariusz C.

Affiliation

Lavigne MD; School of Pharmacy and Biomedical Sciences, Institute of Biomedical and Biomolecular Sciences, University of Portsmouth, UK.

FASEB J ; 22(6): 2097-107, 2008 Jun.

Article in En | MEDLINE | ID: mdl-18202142

Subject(s)

Cell Nucleus/metabolism; Fabry Disease/therapy; Genetic Therapy/methods; Genetic Vectors; alpha-Galactosidase/administration & dosage; Animals; Deoxyribonucleases, Type I Site-Specific; Disease Models, Animal; Gene Transfer Techniques; Mice; Muscle, Skeletal

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Full text: 1 Database: MEDLINE Main subject: Genetic Therapy / Cell Nucleus / Fabry Disease / Alpha-Galactosidase / Genetic Vectors Type of study: Prognostic_studies Limits: Animals Language: En Year: 2008 Type: Article

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