Discovery of novel FMS kinase inhibitors as anti-inflammatory agents.

Illig, Carl R; Chen, Jinsheng; Wall, Mark J; Wilson, Kenneth J; Ballentine, Shelley K; Rudolph, M Jonathan; DesJarlais, Renee L; Chen, Yanmin; Schubert, Carsten; Petrounia, Ioanna; Crysler, Carl S; Molloy, Christopher J; Chaikin, Margery A; Manthey, Carl L; Player, Mark R; Tomczuk, Bruce E; Meegalla, Sanath K

Illig, Carl R; Chen, Jinsheng; Wall, Mark J; Wilson, Kenneth J; Ballentine, Shelley K; Rudolph, M Jonathan; DesJarlais, Renee L; Chen, Yanmin; Schubert, Carsten; Petrounia, Ioanna; Crysler, Carl S; Molloy, Christopher J; Chaikin, Margery A; Manthey, Carl L; Player, Mark R; Tomczuk, Bruce E; Meegalla, Sanath K.

Affiliation

Illig CR; Johnson & Johnson Pharmaceutical Research & Development, Welsh & McKean Roads, Spring House, PA 19477, USA.

Bioorg Med Chem Lett ; 18(5): 1642-8, 2008 Mar 01.

Article in En | MEDLINE | ID: mdl-18242992

Subject(s)

Anti-Inflammatory Agents/chemistry; Anti-Inflammatory Agents/pharmacology; Receptor, Macrophage Colony-Stimulating Factor/antagonists & inhibitors; Animals; Arthritis/chemically induced; Arthritis/drug therapy; Collagen; Dose-Response Relationship, Drug; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Time Factors

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Full text: 1 Database: MEDLINE Main subject: Receptor, Macrophage Colony-Stimulating Factor / Anti-Inflammatory Agents Type of study: Prognostic_studies Limits: Animals Language: En Year: 2008 Type: Article

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