Identification of a novel asthma susceptibility gene on chromosome 1qter and its functional evaluation.

White, Julia H; Chiano, Mathias; Wigglesworth, Mark; Geske, Robert; Riley, John; White, Nicola; Hall, Simon; Zhu, Guohua; Maurio, Frank; Savage, Tony; Anderson, Wayne; Cordy, Joanna; Ducceschi, Melissa; Vestbo, Jorgen; Pillai, Sreekumar G

White, Julia H; Chiano, Mathias; Wigglesworth, Mark; Geske, Robert; Riley, John; White, Nicola; Hall, Simon; Zhu, Guohua; Maurio, Frank; Savage, Tony; Anderson, Wayne; Cordy, Joanna; Ducceschi, Melissa; Vestbo, Jorgen; Pillai, Sreekumar G.

Affiliation

White JH; Molecular Discovery Research, GlaxoSmithKline Research and Development, RTP, NC, USA/Stevenage, UK.

Hum Mol Genet ; 17(13): 1890-903, 2008 Jul 01.

Article in En | MEDLINE | ID: mdl-18344558

Subject(s)

Adaptor Proteins, Signal Transducing/genetics; Asthma/genetics; Chromosomes, Human, Pair 1/genetics; Genetic Predisposition to Disease; Rod Opsins/genetics; Adaptor Proteins, Signal Transducing/metabolism; Adolescent; Adult; Asthma/physiopathology; Cell Line; Child; Chromosome Mapping; Female; Genetic Linkage; Humans; Lung/metabolism; Lung/physiopathology; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Polymorphism, Genetic; RNA, Small Interfering/genetics; Rod Opsins/metabolism; White People/genetics

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Full text: 1 Database: MEDLINE Main subject: Asthma / Chromosomes, Human, Pair 1 / Rod Opsins / Genetic Predisposition to Disease / Adaptor Proteins, Signal Transducing Type of study: Diagnostic_studies / Prognostic_studies Limits: Adolescent / Adult / Child / Female / Humans / Male / Middle aged Language: En Year: 2008 Type: Article

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