Dynamic interactions between the promoter and terminator regions of the mammalian BRCA1 gene.

Tan-Wong, Sue Mei; French, Juliet D; Proudfoot, Nicholas J; Brown, Melissa A

Tan-Wong, Sue Mei; French, Juliet D; Proudfoot, Nicholas J; Brown, Melissa A.

Affiliation

Tan-Wong SM; Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, United Kingdom.

Proc Natl Acad Sci U S A ; 105(13): 5160-5, 2008 Apr 01.

Article in En | MEDLINE | ID: mdl-18375767

Subject(s)

BRCA1 Protein/genetics; DNA/genetics; DNA/metabolism; Gene Expression Regulation; Nucleic Acid Conformation; Promoter Regions, Genetic/genetics; Terminator Regions, Genetic/genetics; Animals; BRCA1 Protein/chemistry; BRCA1 Protein/metabolism; Breast/metabolism; Breast Neoplasms/genetics; Breast Neoplasms/metabolism; Cell Line, Tumor; Chromatin/genetics; Chromatin/metabolism; DNA/chemistry; Estrogens/metabolism; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred C57BL; Models, Molecular; Transcription, Genetic/genetics

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Full text: 1 Database: MEDLINE Main subject: DNA / Gene Expression Regulation / Promoter Regions, Genetic / Terminator Regions, Genetic / BRCA1 Protein / Nucleic Acid Conformation Limits: Animals / Female / Humans Language: En Year: 2008 Type: Article

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