Evaluation of population pharmacokinetics and exposure-response relationship with coadministration of amlodipine besylate and olmesartan medoxomil.

Rohatagi, Shashank; Carrothers, Timothy J; Kshirsagar, Smita; Khariton, Tatiana; Lee, James; Salazar, Daniel

Rohatagi, Shashank; Carrothers, Timothy J; Kshirsagar, Smita; Khariton, Tatiana; Lee, James; Salazar, Daniel.

Affiliation

Rohatagi S; Daiichi Sankyo, Inc, Parsippany, NJ, USA. srohatagi@dsus.com

J Clin Pharmacol ; 48(7): 823-36, 2008 Jul.

Article in En | MEDLINE | ID: mdl-18490496

Subject(s)

Amlodipine/pharmacokinetics; Antihypertensive Agents/pharmacokinetics; Imidazoles/pharmacokinetics; Tetrazoles/pharmacokinetics; Adult; Age Factors; Amlodipine/administration & dosage; Antihypertensive Agents/administration & dosage; Drug Therapy, Combination; Female; Humans; Hypertension/drug therapy; Imidazoles/administration & dosage; Male; Middle Aged; Models, Biological; Olmesartan Medoxomil; Sex Characteristics; Tetrazoles/administration & dosage

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Full text: 1 Database: MEDLINE Main subject: Tetrazoles / Amlodipine / Imidazoles / Antihypertensive Agents Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Year: 2008 Type: Article

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