Pathology-specific effects of the IKur/Ito/IK,ACh blocker AVE0118 on ion channels in human chronic atrial fibrillation.

Christ, T; Wettwer, E; Voigt, N; Hála, O; Radicke, S; Matschke, K; Várro, A; Dobrev, D; Ravens, U

Christ, T; Wettwer, E; Voigt, N; Hála, O; Radicke, S; Matschke, K; Várro, A; Dobrev, D; Ravens, U.

Affiliation

Christ T; Department of Pharmacology and Toxicology, Dresden University of Technology, Dresden, Germany.

Br J Pharmacol ; 154(8): 1619-30, 2008 Aug.

Article in En | MEDLINE | ID: mdl-18536759

Subject(s)

Atrial Fibrillation/drug therapy; Biphenyl Compounds/pharmacology; Potassium Channel Blockers/pharmacology; Potassium Channels/drug effects; Action Potentials/drug effects; Aged; Atrial Fibrillation/physiopathology; Chronic Disease; Electrophysiology; Female; Heart Atria/cytology; Heart Atria/pathology; Humans; In Vitro Techniques; Male; Microelectrodes; Myocytes, Cardiac/drug effects; Myocytes, Cardiac/pathology; Patch-Clamp Techniques; Potassium Channels/metabolism

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Full text: 1 Database: MEDLINE Main subject: Atrial Fibrillation / Biphenyl Compounds / Potassium Channels / Potassium Channel Blockers Limits: Aged / Female / Humans / Male Language: En Year: 2008 Type: Article

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