How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways.

Simon, Sidney A; Liedtke, Wolfgang

Simon, Sidney A; Liedtke, Wolfgang.

Affiliation

Simon SA; Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27708, USA. sas@neuro.duke.edu

J Clin Invest ; 118(7): 2383-6, 2008 Jul.

Article in En | MEDLINE | ID: mdl-18568080

Subject(s)

Nicotiana; Oxidants/toxicity; Smoke; Transient Receptor Potential Channels/physiology; Acrolein/toxicity; Air Pollutants/toxicity; Aldehydes/toxicity; Animals; Calcium Channels/physiology; Guinea Pigs; Mice; Models, Biological; Neurogenic Inflammation/chemically induced; Neurogenic Inflammation/physiopathology; Neurons, Afferent/drug effects; Neurons, Afferent/physiology; Respiratory Hypersensitivity/chemically induced; Respiratory Hypersensitivity/physiopathology; Respiratory System/drug effects; Respiratory System/innervation; Respiratory System/physiopathology; Respiratory Tract Diseases/chemically induced; Respiratory Tract Diseases/physiopathology; TRPA1 Cation Channel; TRPV Cation Channels/physiology; Transient Receptor Potential Channels/agonists; Transient Receptor Potential Channels/antagonists & inhibitors

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Full text: 1 Database: MEDLINE Main subject: Smoke / Nicotiana / Oxidants / Transient Receptor Potential Channels Type of study: Prognostic_studies Limits: Animals Language: En Year: 2008 Type: Article

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