Acute neonatal glucocorticoid exposure produces selective and rapid cerebellar neural progenitor cell apoptotic death.

Noguchi, K K; Walls, K C; Wozniak, D F; Olney, J W; Roth, K A; Farber, N B

Noguchi, K K; Walls, K C; Wozniak, D F; Olney, J W; Roth, K A; Farber, N B.

Affiliation

Noguchi KK; Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110-1093, USA. noguchik@wustl.edu

Cell Death Differ ; 15(10): 1582-92, 2008 Oct.

Article in En | MEDLINE | ID: mdl-18600230

Subject(s)

Apoptosis/drug effects; Cerebellum/growth & development; Glucocorticoids/pharmacology; Neurons/drug effects; Neurons/physiology; Stem Cells/drug effects; Stem Cells/physiology; Animals; Apoptosis/physiology; Apoptosis Regulatory Proteins; Behavior, Animal/physiology; Cerebellum/cytology; Child; Dexamethasone/pharmacology; Dose-Response Relationship, Drug; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity/physiology; Neurons/cytology; Signal Transduction/physiology; Stem Cells/cytology; Tumor Suppressor Proteins/genetics; Tumor Suppressor Proteins/metabolism; bcl-2 Homologous Antagonist-Killer Protein/genetics; bcl-2 Homologous Antagonist-Killer Protein/metabolism; bcl-2-Associated X Protein/genetics; bcl-2-Associated X Protein/metabolism

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Full text: 1 Database: MEDLINE Main subject: Stem Cells / Cerebellum / Apoptosis / Glucocorticoids / Neurons Limits: Animals / Child / Humans Language: En Year: 2008 Type: Article

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