Design and synthesis of medium-ring lactam libraries inspired by octalactin a. A convergent-divergent approach.

Brown, Neil; Gao, Ge; Minatoya, Machiko; Xie, Baohan; Vandervelde, David; Lushington, Gerald H; Perchellet, Jean-Pierre H; Perchellet, Elisabeth M; Crow, Kyle R; Buszek, Keith R

Brown, Neil; Gao, Ge; Minatoya, Machiko; Xie, Baohan; Vandervelde, David; Lushington, Gerald H; Perchellet, Jean-Pierre H; Perchellet, Elisabeth M; Crow, Kyle R; Buszek, Keith R.

Affiliation

Brown N; Department of Chemistry, University of Missouri, 205 Spencer Chemical Laboratories, 5100 Rockhill Road, Kansas City, Missouri 64110, USA.

J Comb Chem ; 10(5): 628-31, 2008.

Article in En | MEDLINE | ID: mdl-18693764

Subject(s)

Anti-Bacterial Agents/pharmacology; Drug Design; Lactams/pharmacology; Lactones/pharmacology; Amines/chemistry; Amino Acids/chemistry; Anti-Bacterial Agents/chemical synthesis; Benzaldehydes/chemistry; Carbamates/chemistry; Cyclization; Lactams/chemical synthesis; Lactones/chemistry; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Chemical; Stereoisomerism; Urea/chemistry

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Full text: 1 Database: MEDLINE Main subject: Drug Design / Lactams / Lactones / Anti-Bacterial Agents Language: En Year: 2008 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Drug Design / Lactams / Lactones / Anti-Bacterial Agents Language: En Year: 2008 Type: Article