Vascular endothelial growth factor receptor-1 contributes to resistance to anti-epidermal growth factor receptor drugs in human cancer cells.

Bianco, Roberto; Rosa, Roberta; Damiano, Vincenzo; Daniele, Gennaro; Gelardi, Teresa; Garofalo, Sonia; Tarallo, Valeria; De Falco, Sandro; Melisi, Davide; Benelli, Roberto; Albini, Adriana; Ryan, Anderson; Ciardiello, Fortunato; Tortora, Giampaolo

Bianco, Roberto; Rosa, Roberta; Damiano, Vincenzo; Daniele, Gennaro; Gelardi, Teresa; Garofalo, Sonia; Tarallo, Valeria; De Falco, Sandro; Melisi, Davide; Benelli, Roberto; Albini, Adriana; Ryan, Anderson; Ciardiello, Fortunato; Tortora, Giampaolo.

Affiliation

Bianco R; Cattedra di Oncologia Medica, Dipartimento di Endocrinologia e Oncologia Molecolare e Clinica, Università di Napoli Federico II, Via S. Pansini 5, Naples, Italy.

Clin Cancer Res ; 14(16): 5069-80, 2008 Aug 15.

Article in En | MEDLINE | ID: mdl-18694994

Subject(s)

Drug Resistance, Neoplasm/physiology; ErbB Receptors/antagonists & inhibitors; Neoplasms/metabolism; Signal Transduction/physiology; Vascular Endothelial Growth Factor Receptor-1/metabolism; Antineoplastic Agents/pharmacology; Blotting, Western; Cell Adhesion/drug effects; Cell Line, Tumor; Cell Movement/drug effects; Cell Proliferation/drug effects; ErbB Receptors/drug effects; Humans; Immunoprecipitation; Neoplasms/drug therapy; Piperidines/pharmacology; Quinazolines/pharmacology; RNA Interference; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Vascular Endothelial Growth Factor Receptor-1/drug effects

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Full text: 1 Database: MEDLINE Main subject: Signal Transduction / Drug Resistance, Neoplasm / Vascular Endothelial Growth Factor Receptor-1 / ErbB Receptors / Neoplasms Limits: Humans Language: En Year: 2008 Type: Article

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