An overview of the relations between polymorphisms in drug metabolising enzymes and drug transporters and survival after cancer drug treatment.

Ekhart, Corine; Rodenhuis, Sjoerd; Smits, Paul H M; Beijnen, Jos H; Huitema, Alwin D R

Ekhart, Corine; Rodenhuis, Sjoerd; Smits, Paul H M; Beijnen, Jos H; Huitema, Alwin D R.

Affiliation

Ekhart C; Department of Pharmacy and Pharmacology, The Netherlands Cancer Institute/Slotervaart Hospital, Louwesweg 6, 1066 EC Amsterdam, The Netherlands. Corine.Ekhart@slz.nl

Cancer Treat Rev ; 35(1): 18-31, 2009 Feb.

Article in En | MEDLINE | ID: mdl-18771857

Subject(s)

Antineoplastic Agents/therapeutic use; Glutathione Transferase/genetics; Membrane Transport Proteins/genetics; Mixed Function Oxygenases/genetics; Neoplasms/drug therapy; Polymorphism, Genetic/genetics; ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics; ATP-Binding Cassette Transporters/genetics; Humans; Neoplasms/genetics; Pharmacogenetics

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Full text: 1 Database: MEDLINE Main subject: Membrane Transport Proteins / Polymorphism, Genetic / Glutathione Transferase / Mixed Function Oxygenases / Neoplasms / Antineoplastic Agents Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: En Year: 2009 Type: Article

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