Synthesis and anticonvulsant activities of N-benzyl (2R)-2-acetamido-3-oxysubstituted propionamide derivatives.

Morieux, Pierre; Stables, James P; Kohn, Harold

Morieux, Pierre; Stables, James P; Kohn, Harold.

Affiliation

Morieux P; Division of Medicinal Chemistry and Natural Products, School of Pharmacy, University of North Carolina, Campus Box 7360, Chapel Hill, NC 27599-7360, USA.

Bioorg Med Chem ; 16(19): 8968-75, 2008 Oct 01.

Article in En | MEDLINE | ID: mdl-18789868

Subject(s)

Acetamides/pharmacology; Anticonvulsants/pharmacology; Acetamides/chemical synthesis; Animals; Anticonvulsants/chemical synthesis; Binding Sites; Lacosamide; Male; Mice; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship

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Full text: 1 Database: MEDLINE Main subject: Acetamides / Anticonvulsants Limits: Animals Language: En Year: 2008 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Acetamides / Anticonvulsants Limits: Animals Language: En Year: 2008 Type: Article