Quantitative mass spectrometry identifies drug targets in cancer stem cell-containing side population.

Steiniger, Sebastian C J; Coppinger, Judith A; Krüger, Jörg A; Yates, John; Janda, Kim D

Steiniger, Sebastian C J; Coppinger, Judith A; Krüger, Jörg A; Yates, John; Janda, Kim D.

Affiliation

Steiniger SC; The Skaggs Institute for Chemical Biology and Department of Chemistry and Immunology, La Jolla, California 92037, USA.

Stem Cells ; 26(12): 3037-46, 2008 Dec.

Article in En | MEDLINE | ID: mdl-18802034

Subject(s)

Drug Screening Assays, Antitumor/methods; Gene Expression Regulation, Neoplastic; Mass Spectrometry/methods; Neoplastic Stem Cells/cytology; Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents/pharmacology; Cell Line, Tumor; DNA-Binding Proteins; Drug Screening Assays, Antitumor/instrumentation; Female; Humans; Mice; Mice, SCID; Nuclear Proteins; Peroxiredoxin VI/biosynthesis; Pyruvate Kinase/biosynthesis; RNA-Binding Proteins; Thymosin/biosynthesis

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Full text: 1 Database: MEDLINE Main subject: Mass Spectrometry / Neoplastic Stem Cells / Drug Screening Assays, Antitumor / Gene Expression Regulation, Neoplastic Limits: Animals / Female / Humans Language: En Year: 2008 Type: Article

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