Differential regulation of peroxisome proliferator-activated receptor (PPAR)-alpha1 and truncated PPARalpha2 as an adaptive response to fasting in the control of hepatic peroxisomal fatty acid beta-oxidation in the hibernating mammal.

El Kebbaj, Zakaria; Andreoletti, Pierre; Mountassif, Driss; Kabine, Mostafa; Schohn, Hervé; Dauça, Michel; Latruffe, Norbert; El Kebbaj, M'hammed Saïd; Cherkaoui-Malki, Mustapha

El Kebbaj, Zakaria; Andreoletti, Pierre; Mountassif, Driss; Kabine, Mostafa; Schohn, Hervé; Dauça, Michel; Latruffe, Norbert; El Kebbaj, M'hammed Saïd; Cherkaoui-Malki, Mustapha.

Affiliation

El Kebbaj Z; Faculté des Sciences Gabriel, Unité Mixté de Recherche 866, Institut National de la Santé et de la Recherche Médicale, Centre de Recherche-Biochimie Métabolique et Nutritionnelle, Université de Bourgogne, Dijon, France.

Endocrinology ; 150(3): 1192-201, 2009 Mar.

Article in En | MEDLINE | ID: mdl-18948393

Subject(s)

Fasting/physiology; Fatty Acids/metabolism; Hibernation/genetics; Liver/metabolism; PPAR alpha/genetics; Rodentia/genetics; Rodentia/metabolism; Adaptation, Physiological/drug effects; Adaptation, Physiological/genetics; Adaptation, Physiological/physiology; Animals; Clofibric Acid/analogs & derivatives; Clofibric Acid/pharmacology; Fasting/metabolism; Fibric Acids; Gene Expression Regulation/drug effects; Hibernation/physiology; Hypolipidemic Agents/pharmacology; Lipid Metabolism/genetics; Mammals; Oxidation-Reduction; PPAR alpha/metabolism; Peroxisomes/metabolism; Protein Isoforms/genetics; Protein Isoforms/metabolism; Transcription Factors/genetics; Transcription Factors/metabolism

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Full text: 1 Database: MEDLINE Main subject: Rodentia / Fasting / PPAR alpha / Fatty Acids / Hibernation / Liver Limits: Animals Language: En Year: 2009 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Rodentia / Fasting / PPAR alpha / Fatty Acids / Hibernation / Liver Limits: Animals Language: En Year: 2009 Type: Article