Vasoactive intestinal peptide decreases MYCN expression and synergizes with retinoic acid in a human MYCN-amplified neuroblastoma cell line.

Chevrier, Lucie; Meunier, Annie-Claire; Cochaud, Stéphanie; Muller, Jean-Marc; Chadéneau, Corinne

Chevrier, Lucie; Meunier, Annie-Claire; Cochaud, Stéphanie; Muller, Jean-Marc; Chadéneau, Corinne.

Affiliation

Chevrier L; KInstitut de Physiologie et Biologie Cellulaires, Université de Poitiers, CNRS, Poitiers, F-86022, France.

Int J Oncol ; 33(5): 1081-9, 2008 Nov.

Article in En | MEDLINE | ID: mdl-18949372

Subject(s)

Antineoplastic Agents/pharmacology; Neuroblastoma/metabolism; Nuclear Proteins/metabolism; Oncogene Proteins/metabolism; Tretinoin/pharmacology; Vasoactive Intestinal Peptide/pharmacology; Carrier Proteins/metabolism; Cell Line, Tumor; Cell Shape/drug effects; Down-Regulation; Drug Synergism; Gene Expression Regulation, Neoplastic/drug effects; Heat-Shock Proteins/metabolism; Humans; Kinetics; N-Myc Proto-Oncogene Protein; Neuroblastoma/genetics; Neuroblastoma/pathology; Nuclear Proteins/genetics; Oncogene Proteins/genetics; RNA, Messenger/metabolism; S-Phase Kinase-Associated Proteins/metabolism

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Database: MEDLINE Main subject: Tretinoin / Vasoactive Intestinal Peptide / Nuclear Proteins / Oncogene Proteins / Neuroblastoma / Antineoplastic Agents Limits: Humans Language: En Year: 2008 Type: Article

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