Cytokines/metabolism; Enzyme Inhibitors/pharmacology; Histone Deacetylase Inhibitors; Hydroxamic Acids/pharmacology; Macrophages/drug effects; Piperidones/pharmacology; Animals; Blotting, Western; Cell Line; Cell Survival/drug effects; Cytokines/blood; Cytokines/genetics; Electrophoretic Mobility Shift Assay; Endotoxemia/blood; Endotoxemia/metabolism; Endotoxemia/pathology; Enzyme Inhibitors/chemistry; Hydroxamic Acids/chemistry; Interleukin-1beta/genetics; Interleukin-1beta/metabolism; Interleukin-6/genetics; Interleukin-6/metabolism; Macrophages/cytology; Macrophages/metabolism; Mice; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinase 3/metabolism; Mitogen-Activated Protein Kinases/metabolism; Molecular Structure; NF-kappa B/metabolism; Nitric Oxide/metabolism; Nitric Oxide Synthase Type II/genetics; Nitric Oxide Synthase Type II/metabolism; Phosphorylation/drug effects; Piperidones/chemistry; Protein Binding/drug effects; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor AP-1/metabolism; Tumor Necrosis Factor-alpha/blood; Tumor Necrosis Factor-alpha/genetics; Tumor Necrosis Factor-alpha/metabolism