Combination therapy with radiation or cisplatin enhances the potency of Ad5/35 chimeric oncolytic adenovirus in a preclinical model of head and neck cancer.

Ganesh, S; Gonzalez-Edick, M; Gibbons, D; Ge, Y; VanRoey, M; Robinson, M; Jooss, K

Ganesh, S; Gonzalez-Edick, M; Gibbons, D; Ge, Y; VanRoey, M; Robinson, M; Jooss, K.

Affiliation

Ganesh S; Cell Genesys Inc, South San Francisco, CA 94080, USA. ganeshshanti@yahoo.com

Cancer Gene Ther ; 16(5): 383-92, 2009 May.

Article in En | MEDLINE | ID: mdl-19011598

Subject(s)

Adenoviridae/physiology; Antineoplastic Agents/therapeutic use; Cisplatin/therapeutic use; Head and Neck Neoplasms/therapy; Oncolytic Virotherapy/methods; Oncolytic Viruses/physiology; Animals; Cell Line, Tumor; Combined Modality Therapy; Head and Neck Neoplasms/drug therapy; Head and Neck Neoplasms/radiotherapy; Humans; Mice; Mice, Inbred Strains

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Full text: 1 Database: MEDLINE Main subject: Adenoviridae / Cisplatin / Oncolytic Viruses / Oncolytic Virotherapy / Head and Neck Neoplasms / Antineoplastic Agents Type of study: Guideline Limits: Animals / Humans Language: En Year: 2009 Type: Article

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