Stereoselective inhibition of serotonin re-uptake and phosphodiesterase by dual inhibitors as potential agents for depression.

Cashman, John R; Voelker, Troy; Johnson, Robert; Janowsky, Aaron

Cashman, John R; Voelker, Troy; Johnson, Robert; Janowsky, Aaron.

Affiliation

Cashman JR; Human BioMolecular Research Institute, 5310 Eastgate Mall, San Diego, CA 92121, USA. jcashman@hbri.org

Bioorg Med Chem ; 17(1): 337-43, 2009 Jan 01.

Article in En | MEDLINE | ID: mdl-19014888

Subject(s)

Antidepressive Agents/chemical synthesis; Phosphodiesterase Inhibitors/chemistry; Selective Serotonin Reuptake Inhibitors/chemistry; Cross-Linking Reagents; Drug Delivery Systems; Drug Synergism; Humans; Inhibitory Concentration 50; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors/pharmacology; Selective Serotonin Reuptake Inhibitors/pharmacology; Stereoisomerism

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Full text: 1 Database: MEDLINE Main subject: Phosphodiesterase Inhibitors / Selective Serotonin Reuptake Inhibitors / Antidepressive Agents Limits: Humans Language: En Year: 2009 Type: Article

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