Telbivudine, a nucleoside analog inhibitor of HBV polymerase, has a different in vitro cross-resistance profile than the nucleotide analog inhibitors adefovir and tenofovir.

Seifer, Maria; Patty, April; Serra, Ilaria; Li, Bin; Standring, David N

Seifer, Maria; Patty, April; Serra, Ilaria; Li, Bin; Standring, David N.

Affiliation

Seifer M; Idenix Pharmaceuticals Inc., 60 Hampshire Street, Cambridge, MA 02139, USA.

Antiviral Res ; 81(2): 147-55, 2009 Feb.

Article in En | MEDLINE | ID: mdl-19028525

Subject(s)

Adenine/analogs & derivatives; Antiviral Agents/pharmacology; Drug Resistance, Viral; Hepatitis B virus/drug effects; Nucleosides/pharmacology; Organophosphonates/pharmacology; Pyrimidinones/pharmacology; Adenine/pharmacology; Amino Acid Substitution/genetics; Cell Line, Tumor; Gene Products, pol/antagonists & inhibitors; Gene Products, pol/genetics; Humans; Microbial Sensitivity Tests; Mutation, Missense; Telbivudine; Tenofovir; Thymidine/analogs & derivatives

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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / Pyrimidinones / Adenine / Hepatitis B virus / Drug Resistance, Viral / Organophosphonates / Nucleosides Limits: Humans Language: En Year: 2009 Type: Article

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