Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation.

Zhu, Liqin; Gibson, Paul; Currle, D Spencer; Tong, Yiai; Richardson, Robert J; Bayazitov, Ildar T; Poppleton, Helen; Zakharenko, Stanislav; Ellison, David W; Gilbertson, Richard J

Zhu, Liqin; Gibson, Paul; Currle, D Spencer; Tong, Yiai; Richardson, Robert J; Bayazitov, Ildar T; Poppleton, Helen; Zakharenko, Stanislav; Ellison, David W; Gilbertson, Richard J.

Affiliation

Zhu L; Department of Developmental Neurobiology, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA.

Nature ; 457(7229): 603-7, 2009 Jan 29.

Article in En | MEDLINE | ID: mdl-19092805

Subject(s)

Antigens, CD/metabolism; Cell Lineage; Cell Transformation, Neoplastic; Glycoproteins/metabolism; Intestine, Small/cytology; Neoplastic Stem Cells/metabolism; Peptides/metabolism; Stem Cells/metabolism; Stem Cells/pathology; AC133 Antigen; Adenoma/genetics; Adenoma/metabolism; Adenoma/pathology; Animals; Antigens, CD/analysis; Antigens, CD/genetics; Biomarkers/analysis; Biomarkers/metabolism; Cells, Cultured; Genes, Reporter/genetics; Glycoproteins/analysis; Glycoproteins/genetics; Intestinal Neoplasms/genetics; Intestinal Neoplasms/metabolism; Intestinal Neoplasms/pathology; Intestine, Small/pathology; Mice; Mutation; Neoplasm Transplantation; Neoplastic Stem Cells/cytology; Neoplastic Stem Cells/pathology; Peptides/analysis; Peptides/genetics; Receptors, G-Protein-Coupled/metabolism; Stem Cells/cytology; Transplantation, Heterologous; Wnt Proteins/metabolism; beta Catenin/genetics; beta Catenin/metabolism

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Peptides / Stem Cells / Neoplastic Stem Cells / Glycoproteins / Antigens, CD / Cell Transformation, Neoplastic / Cell Lineage / Intestine, Small Limits: Animals Language: En Year: 2009 Type: Article

Fulltext

XML

PubMed Links

Search on Google