Adenosquamous carcinoma of the pancreas harbors KRAS2, DPC4 and TP53 molecular alterations similar to pancreatic ductal adenocarcinoma.

Brody, Jonathan R; Costantino, Christina L; Potoczek, Magdalena; Cozzitorto, Joseph; McCue, Peter; Yeo, Charles J; Hruban, Ralph H; Witkiewicz, Agnieszka K

Brody, Jonathan R; Costantino, Christina L; Potoczek, Magdalena; Cozzitorto, Joseph; McCue, Peter; Yeo, Charles J; Hruban, Ralph H; Witkiewicz, Agnieszka K.

Affiliation

Brody JR; Department of Surgery, Thomas Jefferson University, Philadelphia, PA, USA.

Mod Pathol ; 22(5): 651-9, 2009 May.

Article in En | MEDLINE | ID: mdl-19270646

Subject(s)

Carcinoma, Adenosquamous/genetics; Carcinoma, Pancreatic Ductal/genetics; DNA-Binding Proteins/genetics; Pancreatic Neoplasms/genetics; Proto-Oncogene Proteins/genetics; Smad4 Protein/genetics; ras Proteins/genetics; Aged; Cadherins/biosynthesis; Carcinoma, Adenosquamous/metabolism; Carcinoma, Adenosquamous/pathology; DNA Mutational Analysis; ErbB Receptors/biosynthesis; Female; Gene Expression; Genes, p16; Humans; Immunohistochemistry; Male; Membrane Proteins/biosynthesis; Middle Aged; Mutation; Pancreatic Neoplasms/metabolism; Pancreatic Neoplasms/pathology; Polymerase Chain Reaction; Proto-Oncogene Proteins p21(ras)

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Pancreatic Neoplasms / Proto-Oncogene Proteins / Carcinoma, Adenosquamous / Ras Proteins / Carcinoma, Pancreatic Ductal / DNA-Binding Proteins / Smad4 Protein Type of study: Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Year: 2009 Type: Article

Fulltext

XML

PubMed Links

Search on Google