Impaired neurogenesis, neuronal loss, and brain functional deficits in the APPxPS1-Ki mouse model of Alzheimer's disease.

Faure, A; Verret, L; Bozon, B; El Tannir El Tayara, N; Ly, M; Kober, F; Dhenain, M; Rampon, C; Delatour, B

Faure, A; Verret, L; Bozon, B; El Tannir El Tayara, N; Ly, M; Kober, F; Dhenain, M; Rampon, C; Delatour, B.

Affiliation

Faure A; CNRS, Lab NAMC, UMR8620, Université Paris Sud, 91405, Orsay, France. alexis.faure@u-psud.fr

Neurobiol Aging ; 32(3): 407-18, 2011 Mar.

Article in En | MEDLINE | ID: mdl-19398247

Subject(s)

Alzheimer Disease; Amyloid beta-Protein Precursor/genetics; Brain/pathology; Brain/physiopathology; Neurogenesis/genetics; Presenilin-1/genetics; Age Factors; Aging; Alzheimer Disease/complications; Alzheimer Disease/genetics; Alzheimer Disease/pathology; Amyloid/metabolism; Analysis of Variance; Animals; Animals, Genetically Modified; Anxiety/etiology; Cognition Disorders/etiology; Disease Models, Animal; Humans; Magnetic Resonance Imaging/methods; Mice; Motor Activity/genetics; Movement Disorders/etiology; Mutation/genetics; Neurologic Examination

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Full text: 1 Database: MEDLINE Main subject: Brain / Amyloid beta-Protein Precursor / Presenilin-1 / Neurogenesis / Alzheimer Disease Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans Language: En Year: 2011 Type: Article

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