Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum.

Tonkin, Christopher J; Carret, Céline K; Duraisingh, Manoj T; Voss, Till S; Ralph, Stuart A; Hommel, Mirja; Duffy, Michael F; Silva, Liliana Mancio da; Scherf, Artur; Ivens, Alasdair; Speed, Terence P; Beeson, James G; Cowman, Alan F

Tonkin, Christopher J; Carret, Céline K; Duraisingh, Manoj T; Voss, Till S; Ralph, Stuart A; Hommel, Mirja; Duffy, Michael F; Silva, Liliana Mancio da; Scherf, Artur; Ivens, Alasdair; Speed, Terence P; Beeson, James G; Cowman, Alan F.

Affiliation

Tonkin CJ; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.

PLoS Biol ; 7(4): e84, 2009 Apr 14.

Article in En | MEDLINE | ID: mdl-19402747

Subject(s)

Antigenic Variation; Gene Silencing; Plasmodium falciparum/genetics; Plasmodium falciparum/immunology; Sirtuins/physiology; Virulence/genetics; Animals; Antigens, Protozoan/biosynthesis; Antigens, Protozoan/genetics; Cell Adhesion/genetics; Erythrocytes/metabolism; Erythrocytes/parasitology; Humans; Malaria, Falciparum/parasitology; Malaria, Falciparum/physiopathology; Membrane Proteins/biosynthesis; Membrane Proteins/genetics; Plasmodium falciparum/metabolism; Promoter Regions, Genetic/physiology; Protozoan Proteins/biosynthesis; Protozoan Proteins/genetics; Protozoan Proteins/physiology; Telomere/metabolism; Transcriptional Activation; Virulence/immunology

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Full text: 1 Database: MEDLINE Main subject: Plasmodium falciparum / Virulence / Antigenic Variation / Gene Silencing / Sirtuins Limits: Animals / Humans Language: En Year: 2009 Type: Article

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