[From liquid crystals to nanoconstructions of DNA].

ABSTRACT

This paper reviews data obtained in our Laboratory in the field of the liquid-crystalline dispersions of the double-stranded nucleic acids (DNA, RNA) and results of the analysis of behavior of these biopolymeric molecules in the quasinematic layers. The fundamental data obtained in this area were used as a background for creation of the DNA nanoconstructions, containing different "guest" (biologically active or/and chemical substances) molecules. Two theoretically possible ways for creation of the DNA nanoconstructions were compared. The unique properties of the nanoconstructions dictating the scope of their practical application are described.