The CD4(+) T-cell response of melanoma patients to a MAGE-A3 peptide vaccine involves potential regulatory T cells.

François, Violaine; Ottaviani, Sabrina; Renkvist, Nicolina; Stockis, Julie; Schuler, Gerold; Thielemans, Kris; Colau, Didier; Marchand, Marie; Boon, Thierry; Lucas, Sophie; van der Bruggen, Pierre

François, Violaine; Ottaviani, Sabrina; Renkvist, Nicolina; Stockis, Julie; Schuler, Gerold; Thielemans, Kris; Colau, Didier; Marchand, Marie; Boon, Thierry; Lucas, Sophie; van der Bruggen, Pierre.

Affiliation

François V; Université Catholique de Louvain, Ludwig Institute for Cancer Research Ltd, Vrije Universiteit Brussel, Brussels, Belgium.

Cancer Res ; 69(10): 4335-45, 2009 May 15.

Article in En | MEDLINE | ID: mdl-19435913

Subject(s)

Antigens, Neoplasm/immunology; CD4-Positive T-Lymphocytes/immunology; Cancer Vaccines/therapeutic use; Melanoma/immunology; Neoplasm Proteins/immunology; T-Lymphocytes, Regulatory/immunology; Vaccines, Subunit/therapeutic use; Antigens, Neoplasm/genetics; Cell Line, Tumor; Clone Cells/immunology; Flow Cytometry; Forkhead Transcription Factors/genetics; Humans; Interleukin-2/pharmacology; Interleukin-4/pharmacology; Interleukin-7/pharmacology; Lymphocyte Activation/drug effects; Neoplasm Proteins/genetics; Peptide Fragments/chemistry; Peptide Fragments/immunology; T-Lymphocytes/immunology

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Full text: 1 Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / T-Lymphocytes, Regulatory / Cancer Vaccines / Vaccines, Subunit / Melanoma / Antigens, Neoplasm / Neoplasm Proteins Limits: Humans Language: En Year: 2009 Type: Article

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