Dipeptidyl nitrile inhibitors of Cathepsin L.
Bioorg Med Chem Lett
; 19(15): 4280-3, 2009 Aug 01.
Article
in En
| MEDLINE
| ID: mdl-19515558
ABSTRACT
A series of potent Cathepsin L inhibitors with good selectivity with respect to other cysteine Cathepsins is described and SAR is discussed with reference to the crystal structure of a protein-ligand complex.
Full text:
1
Database:
MEDLINE
Main subject:
Cathepsin L
/
Nitriles
Limits:
Animals
/
Humans
Language:
En
Year:
2009
Type:
Article