Expression of esophageal cancer related gene 4 (ECRG4), a novel tumor suppressor gene, in esophageal cancer and its inhibitory effect on the tumor growth in vitro and in vivo.

Li, Lin-Wei; Yu, Xi-Ying; Yang, Yang; Zhang, Chun-Peng; Guo, Li-Ping; Lu, Shih-Hsin

Li, Lin-Wei; Yu, Xi-Ying; Yang, Yang; Zhang, Chun-Peng; Guo, Li-Ping; Lu, Shih-Hsin.

Affiliation

Li LW; State Key Laboratory of Molecular Oncology and Department of Etiology and Carcinogenesis, Cancer Institute & Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.

Int J Cancer ; 125(7): 1505-13, 2009 Oct 01.

Article in En | MEDLINE | ID: mdl-19521989

Subject(s)

Biomarkers, Tumor/genetics; Carcinoma, Squamous Cell/genetics; Esophageal Neoplasms/genetics; Genes, Tumor Suppressor; Neoplasm Proteins/genetics; Aged; Biomarkers, Tumor/isolation & purification; Blotting, Western; Carcinoma, Squamous Cell/metabolism; Carcinoma, Squamous Cell/pathology; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2/metabolism; DNA Methylation; Esophageal Neoplasms/metabolism; Esophageal Neoplasms/pathology; Female; Flow Cytometry; Gene Silencing; Humans; Immunohistochemistry; Male; Middle Aged; Multivariate Analysis; NF-kappa B/metabolism; Neoplasm Proteins/isolation & purification; Prognosis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Transfection; Tumor Suppressor Proteins

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Full text: 1 Database: MEDLINE Main subject: Esophageal Neoplasms / Carcinoma, Squamous Cell / Biomarkers, Tumor / Genes, Tumor Suppressor / Neoplasm Proteins Type of study: Etiology_studies / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Year: 2009 Type: Article

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