Inhibition of autophagy induced by proteasome inhibition increases cell death in human SHG-44 glioma cells.

Ge, Peng-Fei; Zhang, Ji-Zhou; Wang, Xiao-Fei; Meng, Fan-Kai; Li, Wen-Chen; Luan, Yong-Xin; Ling, Feng; Luo, Yi-Nan

Ge, Peng-Fei; Zhang, Ji-Zhou; Wang, Xiao-Fei; Meng, Fan-Kai; Li, Wen-Chen; Luan, Yong-Xin; Ling, Feng; Luo, Yi-Nan.

Affiliation

Ge PF; [1] Department of Neurosurgery, 1st Hospital of Jilin University, Changchun, Jilin 130021, China [2] Department of Neurosurgery, Xuanwu Hospital of Capital University of Medical Science, Beijing 100053, China.

Acta Pharmacol Sin ; 30(7): 1046-52, 2009 Jul.

Article in En | MEDLINE | ID: mdl-19575007

Subject(s)

Autophagy/physiology; Cell Death/physiology; Glioma; Proteasome Inhibitors; Animals; Apoptosis Regulatory Proteins/metabolism; Beclin-1; Cell Cycle/physiology; Cell Line, Tumor/drug effects; Cysteine Proteinase Inhibitors/metabolism; Cysteine Proteinase Inhibitors/pharmacology; Glioma/metabolism; Glioma/pathology; Glioma/ultrastructure; Humans; Leupeptins/metabolism; Leupeptins/pharmacology; Membrane Proteins/metabolism; Microtubule-Associated Proteins/metabolism; Proteasome Endopeptidase Complex/metabolism

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Full text: 1 Database: MEDLINE Main subject: Autophagy / Cell Death / Proteasome Inhibitors / Glioma Limits: Animals / Humans Language: En Year: 2009 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Autophagy / Cell Death / Proteasome Inhibitors / Glioma Limits: Animals / Humans Language: En Year: 2009 Type: Article