Thrombospondin-1 (TSP-1) up-regulates tissue inhibitor of metalloproteinase-1 (TIMP-1) production in human tumor cells: exploring the functional significance in tumor cell invasion.

John, Anitha S; Hu, Xioulong; Rothman, Vicki L; Tuszynski, George P

John, Anitha S; Hu, Xioulong; Rothman, Vicki L; Tuszynski, George P.

Affiliation

John AS; Children's Hospital of Philadelphia, Department of Pediatric Cardiology, Philadelphia, PA 19104, USA.

Exp Mol Pathol ; 87(3): 184-8, 2009 Dec.

Article in En | MEDLINE | ID: mdl-19747478

Subject(s)

Breast Neoplasms/pathology; Carcinoma/pathology; Prostatic Neoplasms/pathology; Thrombospondin 1/metabolism; Tissue Inhibitor of Metalloproteinase-1/biosynthesis; Breast Neoplasms/metabolism; Carcinoma/metabolism; Cell Line, Tumor; Female; Humans; Male; Matrix Metalloproteinase 9/metabolism; Neoplasm Invasiveness; Prostatic Neoplasms/metabolism; Thrombospondin 1/pharmacology; Up-Regulation

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Full text: 1 Database: MEDLINE Main subject: Prostatic Neoplasms / Breast Neoplasms / Carcinoma / Tissue Inhibitor of Metalloproteinase-1 / Thrombospondin 1 Limits: Female / Humans / Male Language: En Year: 2009 Type: Article

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