Cell division autoantigen 1 plays a profibrotic role by modulating downstream signalling of TGF-beta in a murine diabetic model of atherosclerosis.

Pham, Y; Tu, Y; Wu, T; Allen, T J; Calkin, A C; Watson, A M; Li, J; Jandeleit-Dahm, K A; Toh, B-H; Cao, Z; Cooper, M E; Chai, Z

Pham, Y; Tu, Y; Wu, T; Allen, T J; Calkin, A C; Watson, A M; Li, J; Jandeleit-Dahm, K A; Toh, B-H; Cao, Z; Cooper, M E; Chai, Z.

Affiliation

Pham Y; Diabetes and Metabolism Division, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria 3004, Australia.

Diabetologia ; 53(1): 170-9, 2010 Jan.

Article in En | MEDLINE | ID: mdl-19847393

Subject(s)

Atherosclerosis/physiopathology; Autoantigens/physiology; Diabetes Mellitus, Experimental/physiopathology; Diabetic Angiopathies/physiopathology; Extracellular Matrix/physiology; Transforming Growth Factor beta/physiology; Animals; Aorta/physiology; Autoantigens/genetics; Blood Glucose/metabolism; Connective Tissue Growth Factor/physiology; Diabetes Mellitus, Experimental/complications; Gene Expression Regulation; Genes, Reporter; Glycated Hemoglobin/metabolism; Lipoproteins/blood; Luciferases/genetics; Mice; RNA, Messenger/genetics; RNA, Small Interfering/genetics; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction/physiology

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Full text: 1 Database: MEDLINE Main subject: Autoantigens / Transforming Growth Factor beta / Diabetes Mellitus, Experimental / Diabetic Angiopathies / Atherosclerosis / Extracellular Matrix Type of study: Prognostic_studies Limits: Animals Language: En Year: 2010 Type: Article

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