Glutathione-S-transferase A3 knockout mice are sensitive to acute cytotoxic and genotoxic effects of aflatoxin B1.

Ilic, Zoran; Crawford, Dana; Vakharia, Dilip; Egner, Patricia A; Sell, Stewart

Ilic, Zoran; Crawford, Dana; Vakharia, Dilip; Egner, Patricia A; Sell, Stewart.

Affiliation

Ilic Z; Ordway Research Institute, Albany, NY 12208, USA. zxi01@health.state.ny.us

Toxicol Appl Pharmacol ; 242(3): 241-6, 2010 02 01.

Article in En | MEDLINE | ID: mdl-19850059

Subject(s)

Aflatoxin B1/toxicity; Carcinoma, Hepatocellular/chemically induced; Glutathione Transferase/genetics; Liver Neoplasms/chemically induced; Mutagens/toxicity; Animals; Blotting, Southern; Blotting, Western; Female; Humans; Male; Mice; Mice, Knockout; Models, Animal; Mutagenicity Tests; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Species Specificity

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Full text: 1 Database: MEDLINE Main subject: Aflatoxin B1 / Carcinoma, Hepatocellular / Glutathione Transferase / Liver Neoplasms / Mutagens Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans / Male Language: En Year: 2010 Type: Article

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