Enhancement of 5-aminopenta-2,4-dienals electrophilicity via activation by O,N-bistrifluoroacetylation. application to an N-acyl Pictet-Spengler reaction.

Nuhant, Philippe; Raikar, Sanjay B; Wypych, Jean-Charles; Delpech, Bernard; Marazano, Christian

Nuhant, Philippe; Raikar, Sanjay B; Wypych, Jean-Charles; Delpech, Bernard; Marazano, Christian.

Affiliation

Nuhant P; Centre de Recherche de Gif, Institut de Chimie des Substances Naturelles, CNRS, Avenue de la Terrasse, 91198 Gif-sur-Yvette Cedex, France. pnuhant@scripps.edu

J Org Chem ; 74(24): 9413-21, 2009 Dec 18.

Article in En | MEDLINE | ID: mdl-19924881

Subject(s)

Aldehydes/chemistry; Alkadienes/chemistry; Alkaloids/chemical synthesis; Carbolines/chemical synthesis; Fluoroacetates; Tetrahydroisoquinolines/chemical synthesis; Acetic Anhydrides; Acetylation; Alkaloids/chemistry; Amination; Carbolines/chemistry; Cyanides/chemistry; Cyclization; Hydrocarbons, Aromatic/chemistry; Indoles/chemistry; Ions; Magnetic Resonance Spectroscopy; Mesylates/chemistry; Nitriles/chemistry; Tetrahydroisoquinolines/chemistry; Trifluoroacetic Acid/chemistry; Tryptamines/chemistry

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Full text: 1 Database: MEDLINE Main subject: Carbolines / Tetrahydroisoquinolines / Aldehydes / Alkadienes / Alkaloids / Fluoroacetates Language: En Year: 2009 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Carbolines / Tetrahydroisoquinolines / Aldehydes / Alkadienes / Alkaloids / Fluoroacetates Language: En Year: 2009 Type: Article