Screening and isolation of a natural dopamine D1 receptor antagonist using cell-based assays.

Yu, Sungryul; Park, Jeong Soo; Paredes, Verenice; Song, Myoung-Chong; Baek, Nam-In; Lee, Sang-Ik; Lim, Jong-Soon; Cho, Nam-Young; Yoon, Jaeseung; Baek, Kwanghee

Yu, Sungryul; Park, Jeong Soo; Paredes, Verenice; Song, Myoung-Chong; Baek, Nam-In; Lee, Sang-Ik; Lim, Jong-Soon; Cho, Nam-Young; Yoon, Jaeseung; Baek, Kwanghee.

Affiliation

Yu S; Graduate School of Biotechnology, Kyung Hee University, Seochundong 1, Yongin-si, Gyeonggi-do 446-701, Republic of Korea.

J Biotechnol ; 145(3): 304-9, 2010 Feb 01.

Article in En | MEDLINE | ID: mdl-19963021

Subject(s)

Biological Assay/methods; Dopamine Antagonists/isolation & purification; Dopamine Antagonists/pharmacology; Drug Evaluation, Preclinical/methods; Receptors, Dopamine D1/antagonists & inhibitors; Animals; Biological Products/analysis; Biological Products/chemistry; Biological Products/pharmacology; CHO Cells; Cricetinae; Cricetulus; Dopamine Antagonists/chemistry; Gleditsia/chemistry; Humans; Ligands; Receptors, Dopamine D1/metabolism; Saponins/chemistry; Saponins/isolation & purification; Saponins/pharmacology; Small Molecule Libraries/analysis; Small Molecule Libraries/pharmacology

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Full text: 1 Database: MEDLINE Main subject: Biological Assay / Receptors, Dopamine D1 / Dopamine Antagonists / Drug Evaluation, Preclinical Type of study: Diagnostic_studies / Screening_studies Limits: Animals / Humans Language: En Year: 2010 Type: Article

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