c-ANCA-induced neutrophil-mediated lung injury: a model of acute Wegener's granulomatosis.

Hattar, K; Oppermann, S; Ankele, C; Weissmann, N; Schermuly, R T; Bohle, R M; Moritz, R; Krögel, B; Seeger, W; Grimminger, F; Sibelius, U; Grandel, U

Hattar, K; Oppermann, S; Ankele, C; Weissmann, N; Schermuly, R T; Bohle, R M; Moritz, R; Krögel, B; Seeger, W; Grimminger, F; Sibelius, U; Grandel, U.

Affiliation

Hattar K; University of Giessen Lung Center, (UGLC), Medical Clinic V, Justus-Liebig University Giessen, Klinikstrasse 36, D-35392, Germany. katja.hattar@innere.med.unigiessen.de

Eur Respir J ; 36(1): 187-95, 2010 Jul.

Article in En | MEDLINE | ID: mdl-20032014

Subject(s)

Acute Lung Injury/immunology; Antibodies, Antineutrophil Cytoplasmic/immunology; Granulomatosis with Polyangiitis/immunology; Neutrophils/immunology; Acute Lung Injury/drug therapy; Acute Lung Injury/pathology; Acute Lung Injury/prevention & control; Animals; Antibodies, Antineutrophil Cytoplasmic/pharmacology; Antibodies, Monoclonal/pharmacology; Disease Models, Animal; Enzyme Inhibitors/pharmacology; Granulomatosis with Polyangiitis/drug therapy; Granulomatosis with Polyangiitis/prevention & control; Humans; Immunoglobulin G/immunology; Immunoglobulin G/pharmacology; Leukocyte Elastase/antagonists & inhibitors; Myeloblastin/immunology; NADPH Oxidases/antagonists & inhibitors; Neutrophil Activation/immunology; Pulmonary Edema/immunology; Pulmonary Edema/prevention & control; Rats; Superoxide Dismutase/analysis; Tumor Necrosis Factor-alpha/immunology; Tumor Necrosis Factor-alpha/pharmacology

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Granulomatosis with Polyangiitis / Antibodies, Antineutrophil Cytoplasmic / Acute Lung Injury / Neutrophils Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2010 Type: Article

Fulltext

XML

PubMed Links

Search on Google