Metformin normalizes type 2 diabetes-induced decrease in cell proliferation and neuroblast differentiation in the rat dentate gyrus.

Hwang, In Koo; Kim, Il Yong; Joo, Eun Jung; Shin, Jae Hoon; Choi, Ji Won; Won, Moo-Ho; Yoon, Yeo Sung; Seong, Je Kyung

Hwang, In Koo; Kim, Il Yong; Joo, Eun Jung; Shin, Jae Hoon; Choi, Ji Won; Won, Moo-Ho; Yoon, Yeo Sung; Seong, Je Kyung.

Affiliation

Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, Seoul National University, Seoul, South Korea.

Neurochem Res ; 35(4): 645-50, 2010 Apr.

Article in En | MEDLINE | ID: mdl-20069360

Subject(s)

Cell Proliferation/drug effects; Dentate Gyrus/drug effects; Diabetes Mellitus, Experimental/pathology; Diabetes Mellitus, Type 2/pathology; Metformin/pharmacology; Neurons/drug effects; Animals; Blood Glucose/analysis; Body Weight/drug effects; Dentate Gyrus/cytology; Doublecortin Protein; Female; Immunohistochemistry; Ki-67 Antigen/metabolism; Male; Rats; Rats, Zucker

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Full text: 1 Database: MEDLINE Main subject: Dentate Gyrus / Cell Proliferation / Diabetes Mellitus, Experimental / Diabetes Mellitus, Type 2 / Metformin / Neurons Limits: Animals Language: En Year: 2010 Type: Article

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